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12/31/1969 03:59 PM
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Ulcerative Colitis: I. the Relationship Between Bacillary Dysentery and Ulcerative Colitis
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ULCERATIVE COLITIS: I. THE RELATIONSHIP BETWEEN BACILLARY DYSENTERY AND ULCERATIVE COLITIS. Research Associate, Department of Public Health and Preventive Medicine, Cornell Medical College; Associate
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12/31/1969 03:59 PM
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Ulcerative Colitis
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One of the enigmas of medicine is the entity of ulcerative colitis. Until its etiology and pathogenesis are established, its management must remain symptomatic. Surgery plays its part in some of these cases. The author, from long experience in this field, offers his thoughts on this facet of management.
(C) 1961 Southern Medical Association
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12/31/1969 03:59 PM
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Treatment of Ulcerative Colitis
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TREATMENT OF ULCERATIVE COLITIS. Soper, Horace September 1936 St. Louis, Missouri uvh 0404522 English Original Article: PDF Only 901-904 Clinical Medicine 227 29 9 Success Turn on more accessible 0
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12/31/1969 03:59 PM
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Chronic Ulcerative Colitis
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CHRONIC ULCERATIVE COLITIS. Riely, Lea April 1935 Oklahoma City, Oklahoma uvh 0404522 English ARTICLE: PDF Only 370-375 Clinical Medicine 468 28 4 Success Turn on more accessible mode Skip to main 0
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12/31/1969 03:59 PM
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Chronic Ulcerative Colitis
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CHRONIC ULCERATIVE COLITIS. From the Roosevelt Hospital, West Fifty-Ninth Street and Ninth Avenue, New York, New York
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12/31/1969 03:59 PM
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Chronic Ulcerative Colitis
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CHRONIC ULCERATIVE COLITIS. From the Department of Medicine, University of Tennessee, Memphis, Tennessee
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12/31/1969 03:59 PM
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Symposium: Psychiatric Aspects of Ulcerative Colitis
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It has long been recognized that ulcerative colitis has a large element of psychiatric interest in its pathogenesis and management. In fact to attempt to treat this disease, either medically or surgically, without recognizing this feature is to court failure. This facet was thoroughly discussed in this Panel Session.
(C) 1967 Southern Medical Association
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12/31/1969 03:59 PM
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Ulcerative Colitis in Children
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Ulcerative colitis occurs more often in infants than is suspected. It may be attended by serious retardation in growth and development. Surgical treatment is generally successful.
(C) 1968 Southern Medical Association
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12/31/1969 03:59 PM
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Ulcerative Colitis in Children
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Ulcerative Colitis in Children. From the Section of Proctology, Department of Surgery, University of Miami School of Medicine, Miami, Fla.
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12/31/1969 03:59 PM
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Chronic Ulcerative Colitis: Etiology
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CHRONIC ULCERATIVE COLITIS: ETIOLOGY. From the Department of Bacteriology, School of Medicine, Emory University, Emory University, Georgia
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12/31/1969 03:59 PM
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Airway Obstruction in Ulcerative Colitis
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colon; We present a case of fulminant ulcerative colitis with associated extraintestinal manifestations, including upper airway obstruction from acute laryngotracheitis. Review of the literature shows few other cases of airway obstruction in chronic inflammatory bowel disease. Aggressive medical management of the underlying inflammatory bowel disease may facilitate a conservative approach to airway management, as in this case.
(C) 1997 Southern Medical Association
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12/31/1969 03:59 PM
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Chronic Ulcerative Colitis: Case Report
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CHRONIC ULCERATIVE COLITIS: CASE REPORT. Garon, Max December 1937 Louisville, Kentucky uvh 0404522 English Original Article: PDF Only 1181-1184 Clinical Medicine 295 30 12 Success Turn on more Skip 0
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12/31/1969 03:59 PM
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Immunologic Aspects of Ulcerative Colitis
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Immunologic Aspects of Ulcerative Colitis. From the Sections of Internal Medicine and Surgery, Mayo Clinic and Foundation, Rochester, Minn 55901
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12/31/1969 03:59 PM
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Personality Patterns and Ulcerative Colitis
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PERSONALITY PATTERNS AND ULCERATIVE COLITIS. July 1954 uvh 0404522 English EDITORIAL DEPARTMENT: PDF Only 701 Clinical Medicine 118 47 7 Success Turn on more accessible mode Skip to main content 0
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12/31/1969 03:59 PM
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Secretory Diarrhea in Ulcerative Colitis
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Secretory Diarrhea in Ulcerative Colitis. GHISHAN, FAYEZ MITROS, FRANK YOUNOSZAI, M. KABIR MD June 1982 Nashville, Tenn Iowa City, Iowa uvh 0404522 English CASE REPORT: PDF Only 764-765 Clinical 6
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12/31/1969 03:59 PM
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Immune Thrombocytopenia and Ulcerative Colitis
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Immune Thrombocytopenia and Ulcerative Colitis. MILLS, MAJ G. M. MC, USA From the Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Tex; and the South Texas Regional Blood Bank, San
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12/31/1969 03:59 PM
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Pulmonary Vasculitis Complicating Ulcerative Colitis
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Pulmonary Vasculitis Complicating Ulcerative Colitis. From the Department of Medicine, Divisions of Pulmonary Diseases and of Digestive Diseases and Nutrition, University of North Carolina School of
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12/31/1969 03:59 PM
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Toxic Megacolon Complicating Chronic Ulcerative Colitis*
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The authors describe the pathologic lesion and consider the pathogenesis of this extremely serious complication of ulcerative colitis. Their results of treatment have been excellent.
(C) 1965 Southern Medical Association
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12/31/1969 03:59 PM
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Problem of Cancer in Ulcerative Colitis
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There are differences of opinion in regard to "prophylactic colectomy" against cancer in instances of chronic ulcerative colitis. The authors consider the prognosis in regard to possible cancer and suggest a conservative attitude if follow-up care can be adequate.
(C) 1968 Southern Medical Association
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12/31/1969 03:59 PM
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The Association of Erythema Nodosum with Ulcerative Colitis
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The Association of Erythema Nodosum with Ulcerative Colitis. From the Mayo Clinic and ***Mavo Foundation, Section of Dermatology, Rochester, Minn. 33901.
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12/31/1969 03:59 PM
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Ileorectal Anastomosis for Intractable Ulcerative Colitis
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Though this procedure has had limited acceptance in the surgical treatment of ulcerative colitis, the authors believe with the proper selection of cases and by use of proper technics it can be a valuable approach in the management of this baffling disease.
(C) 1965 Southern Medical Association
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12/31/1969 03:59 PM
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Surgical Management of Anorectal Complications of Chronic Ulcerative Colitis
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Several complications of ulcerative colitis may show themselves during the course of disease. They must be recognized and be thoroughly considered from the standpoint of surgical management.
(C) 1961 Southern Medical Association
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12/31/1969 03:59 PM
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Surgical Management of Chronic Ulcerative Colitis
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SURGICAL MANAGEMENT OF CHRONIC ULCERATIVE COLITIS.
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12/31/1969 03:59 PM
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Some Psychologic Considerations in the Medical Management of Ulcerative Colitis
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Some Psychologic Considerations in the Medical Management of Ulcerative Colitis. From the Department of Psychiatry, University of Texas Symposium: Psychiatric Aspects of Ulcerative Colitis: PDF Only
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12/31/1969 03:59 PM
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Medical Management of Chronic Ulcerative Colitis
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MEDICAL MANAGEMENT OF CHRONIC ULCERATIVE COLITIS.
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12/31/1969 03:59 PM
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Discontinuous Appendiceal Involvement in Ulcerative Colitis
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DISCONTINUOUS APPENDICEAL INVOLVEMENT IN ULCERATIVE COLITIS. Departments of Colorectal Surgery and Pathology, Ochsner Clinic, New Orleans, La.
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12/31/1969 03:59 PM
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The Role of the Surgeon in Chronic Ulcerative Colitis
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THE ROLE OF THE SURGEON IN CHRONIC ULCERATIVE COLITIS.
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12/31/1969 03:59 PM
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Toxic Megacolon After Proctosigmoidoscopy in ulcerative Colitis
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Toxic Megacolon After Proctosigmoidoscopy in ulcerative Colitis.
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12/31/1969 03:59 PM
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Chronic Ulcerative Colitis: Vaccine Therapy in Sixty-Six Cases
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CHRONIC ULCERATIVE COLITIS: VACCINE THERAPY IN SIXTY-SIX CASES. Department of Gastro-Enterology, Baylor University College of Medicine, Dallas, Tex.
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12/31/1969 03:59 PM
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Adverse Reactions to Salicylazosulfapyridine (Azulfidine) in the Treatment of Ulcerative Colitis
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Though sulfonamides have a place in the management of ulcerative colitis, their use is not without hazard as has been documented in this report.
(C) 1968 Southern Medical Association
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12/31/1969 03:59 PM
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The Surgical Treatment of Chronic Ulcerative Colitis
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THE SURGICAL TREATMENT OF CHRONIC ULCERATIVE COLITIS.
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12/31/1969 03:59 PM
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Azulfidine Therapy for Ulcerative Colitis in Infancy
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Azulfidine Therapy for Ulcerative Colitis in Infancy.
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12/31/1969 03:59 PM
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Ulcerative Colitis Complicated by Autoimmune Hemolytic Anemia
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Ulcerative Colitis Complicated by Autoimmune Hemolytic Anemia. From the Department of Medicine, Divisions of Gastroenterology and Hematology, University of Texas Health Science Center, and Surgical
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12/31/1969 03:59 PM
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Role of the Surgeon in the Treatment of Chronic Ulcerative Colitis
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The management of chronic ulcerative colitis, though successful by a medical regimen in many instances, often requires surgical intervention for permanent control or to save life. The author outlines the indications for surgical attack and the technics most appropriate.
(C) 1963 Southern Medical Association
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12/31/1969 03:59 PM
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Vogt-Koyanagi-Harada Syndrome and Ulcerative Colitis
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The Vogt-Koyanagi-Harada (VKH) syndrome is an uncommon disorder characterized by uveitis and neurologic and cutaneous abnormalities, including tinnitus, vertigo, headache, meningoencephalitis, vitiligo, alopecia, and poliosis. The VKH syndrome has been reported to occur in association with other autoimmune disorders. We report a case of a patient with severe ulcerative colitis who developed VKH syndrome. We postulate that the patient's history of a traumatic brain injury might have been responsible for an abnormal "immunologic milieu" and the occurrence of ulcerative colitis, VKH syndrome, and severe reactive arthritis.
(C) 2004 Southern Medical Association
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12/31/1969 03:59 PM
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Evaluation of the Newer Therapy of Ulcerative Colitis
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EVALUATION OF THE NEWER THERAPY OF ULCERATIVE COLITIS. From the Division of Medicine, Mayo Clinic, Rochester, Minnesota
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12/31/1969 03:59 PM
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Surgical Treatment of Ulcerative Colitis: Problems of the Ileostomy
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In many patients having ulcerative colitis there comes a time when surgical interference must be considered. The indications and methods of attack are presented by the authors. It appears much is to be said for a one-stage ileostomy and colectomy for acute exacerbation of ulcerative colitis
(C) 1957 Southern Medical Association
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12/31/1969 03:59 PM
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Idiopathic Dilation of the Colon in Fulminant Ulcerative Colitis
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These case reports call attention to a serious complication of ulcerative colitis.
(C) 1965 Southern Medical Association
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12/31/1969 03:59 PM
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The Clinical Course of Idiopathic Ulcerative Colitis: Prognostic Implications
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THE CLINICAL COURSE OF IDIOPATHIC ULCERATIVE COLITIS: PROGNOSTIC IMPLICATIONS. From the Departments of Medicine and Radiology, Duke University School of Medicine, Durham, North Carolina
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12/31/1969 03:59 PM
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The Significance of Granulomatous Changes in the Colon in Ulcerative Colitis
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This paper differentiates between ulcerative colitis with and without granulomatous lesions. Not only are the pathologic findings different, but clinical studies and information point to probable differing disease entities. What the implications are in the matter of treatment are not clear as yet.
(C) 1963 Southern Medical Association
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12/31/1969 03:59 PM
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The Relationship of Experimental Ulcerative Colitis to the Human Disease
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The author reviews technics of producing "ulcerative colitis" in experimental animals and its therapy. Comparisons are made with the human variety.
(C) 1965 Southern Medical Association
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12/31/1969 03:59 PM
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Current Status of Sphincter-Saving Operations for Chronic Ulcerative Colitis
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When surgery is demanded by the course of a patient with ulcerative colitis, the sphincter mechanism can be spared. The straight ileoanal anastomosis without a reservoir has not been satisfactory for adults because of frequent diarrheal stools. The ileorectal anastomosis has the advantage of minimal morbidity, but the patient is not totally cured, because the diseased rectum is still in place. The pouch pull-through procedure has an increased morbidity, but the patient is cured of ulcerative colitis. The anastomotic stricture rate is 7% to 15% and the failure rate, 2% to 6%. Inflammation of the pouch or reservoir occurs in 5% to 19%. There have been no deaths in the reviewed series. As the details of the pouch pull-through procedure are refined, this operation will become the choice for treatment of ulcerative colitis.
(C) 1985 Southern Medical Association
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12/31/1969 03:59 PM
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One Stage Colectomy, Proctectomy and Ileostomy for Diffuse Ulcerative Colitis
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The surgical attack on ulcerative colitis has become more bold in recent years with antibiotics and a better understanding of fluid and electrolyte balance. The author proposes a one stage operation be used when the indications for surgery are present.
(C) 1960 Southern Medical Association
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12/31/1969 03:59 PM
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Present Status of Hormonal and Drug Therapy of Ulcerative Colitis
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Present Status of Hormonal and Drug Therapy of Ulcerative Colitis. From Section of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn.
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12/31/1969 03:59 PM
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Radiologic Spectrum of Polypoid Lesions in Ulcerative Colitis and Crohn's Disease
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Various types of polypoid lesions are found in patients with ulcerative colitis and Crohn's disease. True adenomatous polyps are rare. In addition to the sessile or pedunculated "pseudopolyps" of inflammatory bowel disease, the lesions may also assume a filiform shape or reach a giant size. These polypoid lesions are inflammatory in nature and therefore have no malignant potential. Awareness of the benign nature of these lesions is important in the management of patients with inflammatory bowel disease. Unnecessary surgery may be prevented by endoscopic biopsy for confirmation of their inflammatory nature. Representative cases illustrate the ability of the double contrast technic to clearly depict these polypoid lesions.
(C) 1981 Southern Medical Association
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12/31/1969 03:59 PM
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Primary Small Cell Undifferentiated Carcinoma of the Rectum Associated With Ulcerative Colitis
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Primary small cell undifferentiated carcinomas (SCUCs) are unusual tumors of the colon and rectum. Histologically, these lesions represent a spectrum of neuroendocrine differentiation, with oat cell carcinoma being the most primitive subtype and carcinoid tumors being the most differentiated. This observation is supported by immunohistochemical and ultrastructural findings. We report a case of SCUC of the rectum in a patient with ulcerative colitis. To date, there have been only two reported cases of primary SCUC associated with ulcerative colitis. Recent theories of tumorigenesis attribute most colorectal cancers to a single, pluripotential mucosal stem cell, regardless of the tumor's histologic type.
(C) 1996 Southern Medical Association
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12/31/1969 03:59 PM
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Adenoacanthoma and Ulcerative Colitis: Case Report and Review of the Literature
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Squamous cell carcinoma and adenoacanthoma of the colon and rectum above the anal verge are uncommon lesions. A total of 48 cases have been reported since 1907: 23 squamous and 25 adenoacanthomas, including the present case. Five of these cases occurred in patients with ulcerative colitis: the present case, one of adenoacanthoma with predominantly keratinizing metastatic lesions and psammoma bodies, and 4 squamous cell carcinomas reported earlier. In addition, 4 of the remaining 43 cases occurred in patients with preceding or concomitant colon disease: one squamous cell lesion and one adenoacanthoma occurred in the cecum of 2 patients at the site of draining sinuses which had developed some years after appendectomies were performed; one squamous cell carcinoma occurred at the site of tuberculomas, and one at the site of schistosomiasis.
(C) 1973 Southern Medical Association
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12/31/1969 03:59 PM
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A Different Therapeutic Approach in Patients with Severe Ulcerative Colitis: Hyperbaric Oxygen Treatment
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such as radiation enterocolitis, CD, and experimental colitis; however, the experience with HBOT in patients with ulcerative colitis (UC) is limited. <link linktype="reference
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12/31/1969 03:59 PM
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Erosive Temporomandibular Joint Involvement: A Rare Manifestation of Arthropathies Associated with Ulcerative Colitis
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as a feature of the spondyloarthropathy of ulcerative colitis. Oral Surg Oral Med Oral Pathol 1982;53 Joint Involvement: A Rare Manifestation of Arthropathies Associated with Ulcerative Colitis.
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12/31/1969 03:59 PM
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Banthine(R) in Reptic Ulcer and Chronic Ulcerative Colitis: Clinical and Experimental Observations
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BANTHINE(R) IN REPTIC ULCER AND CHRONIC ULCERATIVE COLITIS: CLINICAL AND EXPERIMENTAL OBSERVATIONS. Medical Service, McGuite Veterans Administration Hospital, and the Department of Medicine, Medical
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12/31/1969 03:59 PM
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Comparison of the Possible Risk Factors of Bone Mineral Density in Subjects with Ulcerative Colitis and Healthy Subjects
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Objective: Inflammatory bowel disease (IBD) is a gastrointestinal system disorder with a variety of causes. The prevalence of reduced bone mineral density (BMD) is greater in people with IBD as compared with healthy individuals. In this study, we aimed to investigate the possible risk factors for low BMD in subjects with ulcerative colitis (UC) and in healthy control subjects.
Subjects and Methods: A total of 40 subjects with UC and 29 healthy subjects were enrolled in the study. Age; sex; body mass index; location and duration of disease; current corticosteroid, azathioprine, or other immunosuppressive medications; smoking; consumption of alcohol, milk, and milk products; menstrual pattern in women; and use of vitamin D, calcium, folic acid, multivitamins, and iron preparations were recorded. BMD was measured by dual-energy x-ray absorptiometry at L2-L4 of the spine and the femoral neck.
Results: The BMD of patients was found to be lower than that in the control group. The T and z scores of the lumbar vertebra and femoral neck were normal in 21 subjects (52.5%). A total of 17 (42.5%) subjects had osteopenia, and 2 (5%) subjects had osteoporosis. Parathyroid hormone, 1,25(OH)2 vitamin D3, osteocalcin, and urinary markers were found to be similar in both groups. There were no significant differences between subjects with UC and subjects in the control group according to age, sex, and conventional risk factors.
Conclusions: The BMD of subjects with UC was found to be lower than that in subjects of similar age and sex in the control group. Our findings suggest that that the disease itself is the most important pathogenic factor contributing to low BMD.
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12/31/1969 03:59 PM
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The Use of the Duodenal Tube in Extreme Cases of Ulcerative Colitis-Some Forms of Parasitic Infection of the Colon, and Post-Operative Ileus
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OF THE DUODENAL TUBE IN EXTREME CASES OF ULCERATIVE COLITIS-SOME FORMS OF PARASITIC INFECTION OF THE COLON Professor of Gastroenterology, New York Polyclinic Medical School and Hospital and Fordham
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12/31/1969 03:59 PM
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Indications for Surgery in Ulcerative Colitis
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INDICATIONS FOR SURGERY IN ULCERATIVE COLITIS. E. Beck, Maj David USAF, MC Wilford Hall USAF Medical Center, Lackland AFB, Texas. JOINT MEETING OF THE SECTIONS ON GASTROENTEROLOGY AND COLON & RECTAL
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12/31/1969 03:59 PM
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Deep Venous Thrombosis (Dvt) in A Child With Ulcerative Colitis (Uc)
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DEEP VENOUS THROMBOSIS (DVT) IN A CHILD WITH ULCERATIVE COLITIS (UC). Jersey City Medical Center, Jersey City, NJ.
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12/31/1969 03:59 PM
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A TRANSFORMING GROWTH FACTOR-[beta]1 RECEPTOR TYPE II MUTATION OCCURS IN ULCERATIVE COLITIS-ASSOCIATED NEOPLASMS
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GROWTH FACTOR-[beta]1 RECEPTOR TYPE II MUTATION OCCURS IN ULCERATIVE COLITIS-ASSOCIATED NEOPLASMS. Departments of Medicine (Gastrointestinal Division), Pathology and Thoracic Surgery, University of
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12/31/1969 03:59 PM
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Ulcerative Proctitis
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Ulcerative proctitis, a nonspecific inflammatory process involving the rectal mucosa but not the mucosa of the sigmoid or more proximal colon, is often diagnosed mistakenly as ulcerative colitis because of similarity in gross and microscopic appearances. Ulcerative proctitis, however, is more benign, symptoms are limited to the rectum (bleeding), extracolonic complications are rare, and there is little if any malignant potential, Prognosis is excellent. Review of 50 cases of ulcerative practitis showed a relationship to emotional tension in over one third of the cases. Effective treatment includes hydrocortisone enemas, salicylazosulfapyridine, and especially reassurance of the limited and benign nature of the disease.
(C) 1974 Southern Medical Association
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12/31/1969 03:59 PM
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Ulceratiye Colitis: Surgical Indications and Alternatives
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colon; Ulcerative colitis is a surgically curable mucosal disease of the colon and rectum. Optimal management of this chronic condition requires close coordination between the patient, surgeon, and primary care provider or gastroenterologist. Knowledge of surgical indications and the operative alternatives available helps to individualize therapy. Acute and chronic indications for surgery and the five surgical methods currently in use are described.
(C) 1994 Southern Medical Association
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12/31/1969 03:59 PM
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Hypoalbuminemia, Ascites, and Pseudomembranous Colitis After Clindamycin Therapy
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THE ADMINISTRATION of certain antibiotics is often followed by diarrhea and, in some cases, by pseudomembranous colitis. Lincomycin has been shown to cause diarrhea in 20% to 50% of those treated orally.1 With prolonged therapy, a clinical picture similar to ulcerative colitis has occurred. Clindamycin, a derivative of lincomycin, reportedly causes only mild gastrointestinal symptoms.2 This case report was prompted by a patient who developed pseudomembranous colitis, hypoalbuminemia, and ascites following clindamycin therapy. Pseudomembranous colitis as a cause of protein loss has received little attention in the medical literature. Severe and even fatal hypoproteinemia secondary to pseudomembranous colitis has been reported.3
(C) 1974 Southern Medical Association
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12/31/1969 03:59 PM
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Fatal Colitis in a Hemophilic Patient With Inhibitor
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PSEUDOMEMBRANOUS ENTEROCOLITIS is a recognized complication resulting from the use of diverse kinds of antibiotics. Recent reports have noted this development following the use of lincomycin and a related antibiotic, clindamycin.1-4 The following report describes a fatal case of colitis associated with an antibiotic program which included clindamycin. Our patient with mild classical hemophilia developed a high level factor VIII inhibitor after major surgery and was successfully managed with a plasma concentrate, activated prothrombin complex (Auto IX*).5 Subsequently he deyeloped an antibiotic-associated hemorrhagic ulcerative colitis. The combination of a severe hemorrhagic colitis coupled with a factor VIII inhibitor proved to be lethal.
(C) 1977 Southern Medical Association
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12/31/1969 03:59 PM
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Pyoderma Gangrenosum
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This progressive necrotizing and ulcerative disease of the skin presents serious problems in management. Its association with chronic ulcerative colitis in many instances offers opportunities for speculation as to its etiology, which is far from clear. Fortunately treatment is successful in most instances with reliance upon sulfonamides, and steroids for the more fulminant manifestations.
(C) 1969 Southern Medical Association
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12/31/1969 03:59 PM
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Inflammatory Bowel Disease-Related Thoracic Aortic Thrombosis
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Arterial and venous thromboembolisms have long been associated with inflammatory bowel disease (IBD) and can cause significant morbidity and mortality. We present a patient with aortic arch thrombosis embolizing to the left lower extremity during hospitalization for active ulcerative colitis (UC). The limb was preserved following emergent embolectomy. Thrombophilia was attributed to UC, as hypercoagulable testing was negative. IBD is certainly a hypercoagulable state, and aggressive thromboembolism prevention should be considered for hospitalized patients with active disease.
(C) 2010 Southern Medical Association
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12/31/1969 03:59 PM
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Special Considerations of Its Treatment
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SPECIAL CONSIDERATIONS OF ITS TREATMENT. Rankin, Fred Johnston, Coleman May 1941 Lexington, Kentucky uvh 0404522 English CHRONIC ULCERATIVE COLITIS: PDF Only 464-470 Miscellaneous Clinical 460 34 5
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12/31/1969 03:59 PM
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Duodenal Obstruction: Unusual Types
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From the Department of Medicine and the Mallinckrodt Institute of Radiology, Washington University School of Medicise. CHRONIC ULCERATIVE COLITIS: PDF Only
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12/31/1969 03:59 PM
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Radical Operation for Severe Varicose Veins and Varicose Ulcer
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RADICAL OPERATION FOR SEVERE VARICOSE VEINS AND VARICOSE ULCER. From the Department of Surgery. Tulane University School of Medicine. CHRONIC ULCERATIVE COLITIS: PDF Only
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12/31/1969 03:59 PM
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Topical Steroids in Diseases of the Colon
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The use of steroids in the form of a rectal instillation may offer a valuable adjunct in the treatment of acute exacerbations of ulcerative colitis.
(C) 1959 Southern Medical Association
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12/31/1969 03:59 PM
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Regional Ileitis
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The authors review their cases and consider the pathogenesis of the disease and its differentiation from ulcerative colitis. Management still is discouraging and usually ends in the use of surgical methods.
(C) 1962 Southern Medical Association
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12/31/1969 03:59 PM
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Current Medical Therapy for Inflammatory Bowel Disease
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Traditional medical therapy for inflammatory bowel disease (IBD) includes corticosteroids and sulfasalazine. In recent years, several mesalamine derivatives of sulfasalazine have become available. These allow delivery of increased dosages of active medication with minimal side effects. Newer steroid preparations, all investigational at this point, likely will offer efficacy similar to that of prednisone but with an improved side effect profile. Immunosuppressive agents, including 6-mercaptopurine, azathioprine, and likely also methotrexate, are beneficial in treating refractory IBD, particularly in patients with chronic steroid dependence. Cyclosporine has been shown to be remarkably effective in delaying colectomy for severe ulcerative colitis, but its long-term role remains uncertain.
(C) 1996 Southern Medical Association
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12/31/1969 03:59 PM
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Technical Complications of Ileostomy
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A review of 45 patients with ileostomy revealed a complication rate of 24%. A higher incidence of complications was seen in those patients who were obese (80%), who had chronic ulcerative colitis (45%), or who had an emergency ileostomy because of a surgical complication (50%). Strict attention to technic should prevent the majority of these complications.
(C) 1980 Southern Medical Association
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12/31/1969 03:59 PM
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Current Surgical Management of Inflammatory Bowel Disease
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colon; When surgery is required for complications of inflammatory bowel disease (IBD) or for failure of medical management, numerous options exist. This review focuses on surgical alternatives, technical considerations, and complications for both routine and unusual problems associated with IBD. Restorative proctocolectomy for chronic ulcerative colitis, intestine-sparing procedures for Crohn's disease, and the management of Crohn's disease in difficult anatomic sites or with unusual complications are discussed.
(C) 1994 Southern Medical Association
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12/31/1969 03:59 PM
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Current Controversies in Pouch Surgery
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Restorative proctocolectomy with ileal pouch anal anastomosis has become the most commonly used procedure for elective treatment of patients with mucosal ulcerative colitis and familial adenomatous polyposis. Since its original description, the procedure has been modified in an attempt to obtain optimal functional results with low morbidity and mortality, and yet provide a cure for the disease. These modifications of the technique are discussed in this review, limited to the current points of controversy. We reviewed the current literature describing restorative proctocolectomy with ileal pouch anal anastomosis. The current "hot topics" for debate are transanal mucosectomy with hand-sewn anastomosis versus the double-stapled technique, the use of diverting ileostomy, indeterminate colitis, the role of laparoscopy, and indications for pouch surgery in the elderly. Longer follow-up of patients and increased knowledge and experience with pouch surgery, coupled with active prospective evaluation of the procedure are required to settle these issues. Patients must be fully informed to understand inherent risks of each choice.
(C) 2003 Southern Medical Association
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12/31/1969 03:59 PM
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Restorative Proctocolectomy: Ochsner Clinic Experience
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Background. Restorative proctocolectomy, a standard operation for ulcerative colitis and familial adenomatous polyposis has significant complications, even in experienced hands.
Methods. We studied surgical outcome by retrospectively reviewing cases of restorative proctocolectomy done at Ochsner Foundation Hospital from 1982 to 1995. Demographic and clinical data from two periods (1982 to 1989 and 1989 to 1995) were compared to determine factors associated with improved outcome.
Results. We performed 145 ileal pouch-anal procedures. In 56 patients, 104 complications occurred. The more recent group had a greater incidence of inflammatory bowel disease, steroid use, and staged operations; reduced operative times and hospital stays; more general but fewer pouch-related complications. Pouch failures were similar for both groups.
Conclusions. Perioperative outcome appeared to be associated with technical experience, improved perioperative care, exclusion of patients with Crohn's disease, judicious surgical reoperation for pouch complications, and use of a 3-stage procedure in malnourished patients or those with acute or toxic colitis.
(C) 2001 Southern Medical Association
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12/31/1969 03:59 PM
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Sexual Function After Abdominoperineal Resection
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A survey of the sexual changes in patients having abdominoperineal resection for ulcerative colitis was made at the Medical College of Georgia. The incidence of impotence in our series is zero. Only one of our female patients had a successful pregnancy. The other women seemed to be hampered by anatomic derangements relating to strictures, adhesions, or dislocation of the uterus, although the precise causes of infertility have not been elucidated. We suggest that in young men, fear of injuring sexuality should not impede selection of appropriate surgical modality. However, we also suggest that the women's risk of postoperative impairment of sexual function is greater than the man's.
(C) 1975 Southern Medical Association
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12/31/1969 03:59 PM
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Serum Lysozyme Activity in Inflammatory Bowel Disease
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Serum lysozyme activity was determined in the sera of 70 patients with inflammatory bowel disease by the lysoplate method. Serum lysozyme levels were significantly elevated only in patients with Crohn's disease of the small bowel. Patients with either granulomatous or ulcerative colitis had serum lysozyme values not different from normals, irrespective of activity of their disease.
(C) 1978 Southern Medical Association
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12/31/1969 03:59 PM
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The Problem of Carcinoma in Inflammatory Disease of the Bowel: Selective Case Experiences
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The authors consider the difficulties in the differentiation of Crohn's disease of the colon from chronic ulcerative colitis. Furthermore, this problem is complicated by the tendency to develop malignancy of the colon in long-standing inflammatory disease. This paper evaluates the relative merits of the several means at hand to aid in definitive diagnosis.
(C) 1972 Southern Medical Association
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12/31/1969 03:59 PM
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Loop IleoStomy: A Reliable Method of Diversion
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colon; Between September 1983 and March 1989, 36 loop ileostomies were performed on 34 patients (16 male and 18 female, mean age 36 years, range 11 to 68). Thirty-two patients had ileoanal pouch procedures (30 for ulcerative colitis and two for familial polyposis). One patient had a low anterior resection and another had a coloanal procedure. By the time of this review, 31 of the loop ileostomies were closed. The average time before closure was 5 months and the average length of follow-up was 37 months. All stomas were brought out through the rectus muscle in the right side of the abdomen, without ileal rotation, mesenteric fixation, or parastomal fascial sutures. A support rod was left in place for 3 to 4 weeks postoperatively. There were no major difficulties with skin irritation or appliance management and no instance of parastomal abscess and stoma retraction. Although no complications related to the ostomy or its closure were encountered in these patients, small bowel obstruction before closure (8 patients) or after takedown (5 patients) of the loop ileostomy required operative correction in one patient in each group.
(C) 1994 Southern Medical Association
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12/31/1969 03:59 PM
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An Unexpected Cause of Elevated Prostate Specific Antigen
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was performed. Histology only showed nonspecific colitis and an adenomatous polyp. He was positive at this time was consistent with ulcerative colitis with goblet cell depletion, chronic inflammatory
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12/31/1969 03:59 PM
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Asacol®-induced Neutropenia Resolution Without the Use of Granulocyte Colony-stimulating Factor
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We report a case of neutropenia and gram-negative septicemia in a 73-year-old male with ulcerative colitis. During the hospital course, medications were adjusted according to rare accounts of drug-induced neutropenia. While the substitution of propafenone for another antiarrhythmic brought about no change in the patient's absolute neutrophil count, the cessation of Asacol® (Warner Chilcott, Rockaway, NJ) was followed by a significant improvement in the neutropenic state. In fact, this neutrophil count continued to trend upward for months following. We thereby conclude that Asacol® carries the potential to induce neutropenia and that this reaction may be reversed in some patients solely by discontinuing the medication and without the aid of stimulating factors such as filgrastim.
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12/31/1969 03:59 PM
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Colonic Pseudo-obstruction in Sickle Cell Disease
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A young Arab woman with sickle cell-[beta]0-thalassemia disease developed acute colonic pseudo-obstruction that became chronic but showed some response to hydroxyurea. There was no evidence of microvascular or macrovascular occlusion. We also report the case of an Arab man with sickle cell anemia who presented with acute colonic pseudo-obstruction from which he recovered completely within a few days. Although the development of pseudo-obstruction in these two cases seems to have been a complication of sickle cell anemia, its pathogenesis remains unclear. There are several reports of ischemic and inflammatory disorders of the colon complicating sickle cell disease; however, these two cases represent the first descriptions of large-bowel pseudo-obstruction in this hemoglobinopathy.
(C) 2003 Southern Medical Association
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12/31/1969 03:59 PM
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Disseminated Nocardia nova Infection
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We report the case of a 61-year-old female with ulcerative colitis on therapy with prednisone and azathioprine. The patient presented with fever, dry cough, a swollen lower extremity, and nodules on the right wrist and the scalp. Computed tomography scans of the head, chest, abdomen, and pelvis revealed multiple lesions. Aspirates and biopsies of the lower extremity cystic lesion, the wrist nodule, and the scalp nodule all grew out
. The patient was treated with high-dose trimethoprim and sulfamethoxazole therapy for one year and made a complete recovery.
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12/31/1969 03:59 PM
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Gastrointestinal Bleeding in Children Presenting to the Emergency Department
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Gastrointestinal Bleeding in Children Presenting to the Emergency Department. 2 (1.3%); anal abscess, 2 (1.3%); ulcerative colitis, 2 (1.3%); mucositis, 2 (1.3%); Meckel
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12/31/1969 03:59 PM
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MEFV Gene Mutations in a Patient with Eosinophilic Gastroenteritis
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Eosinophilic gastroenteritis (EG) is an uncommon gastrointestinal disease affecting both children and adults. The underlying molecular mechanism predisposing to the clinical manifestation of eosinophilic gastroenteritis is unknown. A 39-year-old man who was followed up with the diagnosis of familial Mediterranean fever (FMF) was admitted to our clinic with diarrhea, abdominal pain, and weight loss. After endoscopic and colonoscopic examinations EG was diagnosed by histopathological examination. Symptoms were resolved with the treatment of budesonide. To our knowledge, this is the first reported case of EG with the MEFV gene mutations in the literature.
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12/31/1969 03:59 PM
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Imiquimod
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From the Department of Medicine, Section of Clinical Pharmacology, University of Missouri-Kansas used to treat rheumatoid arthritis and ulcerative colitis.<text
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12/31/1969 03:59 PM
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Black Strap Molasses for the Treatment of Inflammatory Bowel Disease-associated Anemia
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Black Strap Molasses for the Treatment of Inflammatory Bowel Disease-associated Anemia. supplements. However, most patients with ulcerative colitis-associated anemia improve on intravenous iron alone
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12/31/1969 03:59 PM
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Anterior Uveitis, Inflammatory Bowel Disease, and Ankylosing Spondylitis in a HLA-B27-positive Woman
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A woman developed anterior uveitis at age 24, inflammatory bowel disease at age 29, and ankylosing spondylitis at age 45 by history. There were frequent recurrences. An HLA-B27 test was positive at age 53. The literature indicates that all of these conditions together in a HLA-B27-positive woman are uncommon. Physicians should be alert to the possibility that a patient might develop another of these associated diseases years after presentation of the first condition and educate their patients accordingly.
(C) 2006 Southern Medical Association
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12/31/1969 03:59 PM
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To Pick a 'Bone' with the Gallbladder
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To Pick a 'Bone' with the Gallbladder. Medical Corps, United States Navy; Naval Medical Center San Diego; San Diego, CA (Lin) Special Sections: Letters to the Editor 1. Nelson JJ, Khan AG. A case of
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12/31/1969 03:59 PM
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Postcholecystectomy Colon Cancer: An Unanswered Question
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Postcholecystectomy Colon Cancer: An Unanswered Question. and cholesterol metabolites of patients with ulcerative colitis, a high-risk group for development of 2. Narisawa T, Magadia NE, Weisburger JH
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12/31/1969 03:59 PM
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Gastrointestinal Kaposi Sarcoma with Appendiceal Involvement
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Kaposi sarcoma is a vascular tumor manifesting as nodular lesions on skin, mucous membranes, or internal organs. This is a case of a 42-year-old human immunodeficiency virus- (HIV) positive bisexual male, not on highly active antiretroviral therapy (HAART) since diagnosis four years ago. He presented with a three-day history of abdominal pains, fever, vomiting, and a one-week history of melena stools. Endoscopy revealed Kaposi sarcoma in the stomach and duodenum. Postendoscopy, he developed acute abdomen. Exploratory laparotomy revealed extensive Kaposi sarcoma of the gastrointestinal tract with appendiceal involvement. The patient underwent appendectomy and had an uneventful recovery. A review of the literature discusses appendiceal Kaposi sarcoma with appendicitis, a rare but critical manifestation of gastrointestinal Kaposi sarcoma.
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12/31/1969 03:59 PM
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Physical Activity Benefits and Risks on the Gastrointestinal System
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Abstract: This review evaluates the current understanding of the benefits and risks of physical activity and exercise on the gastrointestinal system. A significant portion of endurance athletes are affected by gastrointestinal symptoms, but most symptoms are transient and do not have long-term consequences. Conversely, physical activity may have a protective effect on the gastrointestinal system. There is convincing evidence that physical activity reduces the risk of colon cancer. The evidence is less convincing for gastric and pancreatic cancers, gastroesophageal reflux disease, peptic ulcer disease, nonalcoholic fatty liver disease, cholelithiasis, diverticular disease, irritable bowel syndrome, and constipation. Physical activity may reduce the risk of gastrointestinal bleeding and inflammatory bowel disease, although this has not been proven unequivocally. This article provides a critical review of the evidence-based literature concerning exercise and physical activity effects on the gastrointestinal system and provides physicians with a better understanding of the evidence behind exercise prescriptions for patients with gastrointestinal disorders. Well-designed prospective randomized trials evaluating the risks and benefits of exercise and physical activity on gastrointestinal disorders are recommended for future research.
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12/31/1969 03:59 PM
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Intestinal Necrosis due to Sodium Polystyrene Sulfonate (Kayexalate) in Sorbitol
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Background: Sodium polystyrene sulfonate (SPS, Kayexalate) has been implicated in the development of intestinal necrosis. Sorbitol, added as a cathartic agent, may be primarily responsible. Previous studies have documented bowel necrosis primarily in postoperative, dialysis, and transplant patients. We sought to identify additional clinical characteristics among patients with probable SPS-induced intestinal necrosis.
Methods: Rhode Island Hospital surgical pathology records were reviewed to identify all gastrointestinal specimens reported as containing SPS crystals from December 1998 to June 2007. Patient demographics, medical comorbidities, and hospital courses of histologically verified cases of intestinal necrosis were extracted from the medical records.
Results: Twenty-nine patients with reports of SPS crystals were identified. Nine cases were excluded as incidental findings with normal mucosa. Nine patients were excluded as their symptoms began before SPS administration or because an alternate etiology for bowel ischemia was identified. Eleven patients had confirmed intestinal necrosis and a temporal relationship with SPS administration suggestive of SPS-induced necrosis. Only 2 patients were postoperative, and only 4 had end-stage renal disease (ESRD). All patients had documented hyperkalemia, received oral SPS, and developed symptoms of intestinal injury between 3 hours and 11 days after SPS administration. Four patients died.
Conclusion: Intestinal ischemia is a recognized risk of SPS in sorbitol. Our series highlights that patients may be susceptible even in the absence of ESRD, surgical intervention, or significant comorbidity.
(C) 2009 Southern Medical Association
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12/31/1969 03:59 PM
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Bullous Pemphigoid After Boiling Water Burn
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Bullous pemphigoid is the most frequent autoimmune blistering disease, usually affecting elderly patients. Most cases are idiopathic. We report a case of bullous pemphigoid developing four weeks after a boiling water burn, initially at the site of the burn, then elsewhere.
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12/31/1969 03:59 PM
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Transient Marked Elevation of Serum CA 19-9 Levels in a Patient with Acute Cholangitis and Biliary Stent
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Transient Marked Elevation of Serum CA 19-9 Levels in a Patient with Acute Cholangitis and male with a medical history of ulcerative colitis, sclerosing cholangitis, and multiple episodes of acute
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12/31/1969 03:59 PM
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Helicobacter pylori and Beta-2 Microglobulin Levels
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Helicobacter pylori and Beta-2 Microglobulin Levels Department of Pathology, Cankiri State Hospital, Cankiri, Turkey (Dincer) Departments of Gastrointestinal Surgery and Gastroenterology, Turkiye
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12/31/1969 03:59 PM
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Microscopic Polyangiitis Presenting with Liver Dysfunction Preceding Rapidly Progressive Necrotizing Glomerulonephritis
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The authors describe a 52-year-old woman diagnosed with microscopic polyangiitis. She presented with abnormal liver function tests accompanied by fever, headache, and fatigue. Two months later, rapidly progressive necrotizing glomerulonephritis developed together with seropositivity for perinuclear antineutrophil cytoplasmic antibody. Although liver dysfunction from microscopic polyangiitis is very rare, especially at presentation, this diagnostic possibility should be kept in mind to permit prompt consideration of steroid therapy.
(C) 2004 Southern Medical Association
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12/31/1969 03:59 PM
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Pneumocystis carinii jiroveci Pneumonia Following Infliximab Infusion for Crohn Disease: Emphasis on Prophylaxis
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Pneumocystis carinii jiroveci Pneumonia Following Infliximab Infusion for Crohn Disease: Emphasis on Prophylaxis. Wright State University School of Medicine, Miami Valley Hospital, Medical Surgical
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12/31/1969 03:59 PM
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Cytomegalovirus Enteritis in Common Variable Immunodeficiency
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A woman with previously undiagnosed common variable immunodeficiency presented with diarrhea and volume depletion. Biopsies from upper and lower endoscopy revealed atrophic gastritis, villous atrophy, and an inflammatory bowel disease-like chronic colitis, with absence of plasma cells in all sites. Cytomegalovirus inclusions were demonstrated in the colon and small bowel mucosa. Despite therapy with intravenous immunoglobulin and ganciclovir, the patient deteriorated rapidly and subsequently died. This case report highlights the potential for cytomegalovirus to cause extensive disease in patients with common variable immunodeficiency and, thus, the importance of considering it in the initial differential diagnosis so that further morbidity and mortality might be prevented.
(C) 2004 Southern Medical Association
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12/31/1969 03:59 PM
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Acute Profound Thrombocytopenia Following Eptifibatide Administration
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Acute Profound Thrombocytopenia Following Eptifibatide Administration. a history of diabetes mellitus, hypertension, ulcerative colitis, and dyslipidemia presented to the emergency
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12/31/1969 03:59 PM
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Diagnosing Irritable Bowel Syndrome: A Changing Clinical Paradigm
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Rather than being a diagnosis of exclusion, irritable bowel syndrome (IBS) is a diagnosis that can be identified by symptom-based criteria. The collection of these criteria by a meticulous history can be enhanced by using various tools. Once a positive diagnosis is made, using clinical criteria for diagnosis, one should look for alarm or warning symptoms or signs, and should characterize the type of bowel habit. Determining whether the condition is a diarrhea-predominant or a constipation-predominant IBS will direct further diagnostic evaluation and management.
Key Points
* IBS is diagnosed by symptom-based clinical criteria.
* A positive diagnosis using clinical criteria can avoid exhaustive diagnostic testing.
* Characterizing the bowel habit as diarrhea- or constipation-predominant will direct further diagnostic evaluation and management.
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12/31/1969 03:59 PM
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Colorectal Cancer Screening: Today and Tomorrow
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Colorectal cancer remains a disease with significant morbidity and mortality. However, the prognosis can be greatly improved with early detection. Here, we review the current screening modalities and guidelines for patients at average, moderate, and high risk for colorectal cancer. New experimental modalities are also introduced.
(C) 2006 Southern Medical Association
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12/31/1969 03:59 PM
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Emphysematous Cystitis in the Absence of Known Risk Factors: An Unusual Clinical Entity
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Emphysematous cystitis is a rare disorder that is usually associated with immunosuppression, poorly controlled diabetes mellitus, and other risk factors such as previous urinary tract infection and/or recent instrumentation of the urinary tract. The case of an 89-year-old woman with emphysematous cystitis who had no evidence of immunodeficiency or other risk factors except for advanced age is reported. A review of the literature on emphysematous cystitis in immunocompetent, nondiabetic individuals is presented.
(C) 2009 Southern Medical Association
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12/31/1969 03:59 PM
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Irritable Bowel Syndrome: A Practical Review
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The epidemiology and current understanding of the pathophysiology of irritable bowel syndrome is reviewed, beginning with a historical perspective. The roles of genetics, environment, allergy, infection and inflammation, bacterial overgrowth, hormones and motility abnormalities are discussed. Using the current evidence-based literature, the practical approach of diagnosis and treatment is outlined, including traditional modalities and newer therapeutic agents such as serotonin modulators.
(C) 2006 Southern Medical Association
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